Li, L., Chen, C. Y., Aldini, G., Johnson, E. J., Rasmussen, H., Yoshida, Y., Niki, E., Blumberg, J. Food Chem 12-15-2012;135(4):2736-2742. Likely not, but overall we still have a way to go when it comes to understanding the full potential of lutein in terms of disease prevention, bioavailability, metabolism and dose-response relationships. View abstract. Arterioscler.Thromb.Vasc.Biol 1997;17(6):1171-1177. Am J Clin Nutr 2006;83(1):163-169. Optom Vis Sci 1997;74:499-504. Nutrition 2012;28(6):605-610. 2007;61(10):1180-1188. Cho, E., Hankinson, S. E., Rosner, B., Willett, W. C., and Colditz, G. A. 2010;93(5):300-308. At this time there isnt a general recommendation for daily intake of lutein or zeaxanthin. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Valero, M. P., Fletcher, A. E., De Stavola, B. L., Vioque, J., and Alepuz, V. C. Vitamin C is associated with reduced risk of cataract in a Mediterranean population. View abstract. Palombo, P., Fabrizi, G., Ruocco, V., Ruocco, E., Fluhr, J., Roberts, R., and Morganti, P. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. Wu J, Cho E, Willett WC, Sastry SM, Schaumberg DA. View abstract. 2013 Feb 15;5(2):543-51. O'Neill, M. E., Carroll, Y., Corridan, B., Olmedilla, B., Granado, F., Blanco, I., van den, Berg H., Hininger, I., Rousell, A. M., Chopra, M., Southon, S., and Thurnham, D. I. View abstract. Eur.J.Clin.Nutr. Treatment of Macular Telangiectasia Type 2 With Carotenoid Supplements Containing Meso-Zeaxanthin: A Pilot Study. WebCommon drugs people take besides Lutein *: Dupixent: 2 people, 18.18%. This includes a 2018 study in which researchers concluded: Dietary lutein supplementation may be a promising alternative and/or adjunct therapeutic candidate against breast cancer.. BMJ 1992;305:335-9. 2014;42(1):25-38. View abstract. Thurnham, D. I., Northrop-Clewes, C. A., Paracha, P. I., and McLoone, U. J. Invest Ophthalmol.Vis.Sci. People who dont eat many vegetable or fruits can probably benefit from supplementing with higher doses, as can older adults, smokers and post-menopausal women. It is certified by the National Eczema Association, meaning it is safe for those with eczema or sensitive skina testament to its mildness. Bone, R. A., Landrum, J. T., Dixon, Z., Chen, Y., and Llerena, C. M. Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Lung cancer mortality and serum levels of carotenoids, retinol, tocopherols, and folic acid in men and women: a case-control study nested in the JACC Study. Photochem.Photobiol. Cancer Epidemiol Biomarkers Prev 2003;12:518-26. Molldrem, K. L., Li, J., Simon, P. W., and Tanumihardjo, S. A. Lutein and beta-carotene from lutein-containing yellow carrots are bioavailable in humans. That said, possible lutein and zeaxanthin side effects can include harmless yellowingof the skin calledcarotenemia and an upset stomach/vomiting if you take too much. 2012;90(5):e399-e403. View abstract. Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes. View abstract. SanGiovanni, J. P. and Neuringer, M. The putative role of lutein and zeaxanthin as protective agents against age-related macular degeneration: promise of molecular genetics for guiding mechanistic and translational research in the field. Williams, M. A., Woelk, G. B., King, I. View abstract. View abstract. View abstract. Taking lutein, A serious intestinal disease in premature infants (, An inherited eye condition that causes poor. Eliassen, A. H., Hendrickson, S. J., Brinton, L. A., Buring, J. E., Campos, H., Dai, Q., Dorgan, J. F., Franke, A. In fact, eye vitamins with lutein are some of the bestvitamins for macular degeneration. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Schweiggert, R. M., Mezger, D., Schimpf, F., Steingass, C. B., and Carle, R. Influence of chromoplast morphology on carotenoid bioaccessibility of carrot, mango, papaya, and tomato. Ferguson, L. R. and Schlothauer, R. C. The potential role of nutritional genomics tools in validating high health foods for cancer control: broccoli as example. Diet and lifestyle correlates of lutein in the blood and diet. Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. USCs observational studies show that people with the highest levels of lutein in the blood experience less plaque buildup in the arteries, while the opposite is also true: The fewer lutein-rich plant foods someone eats, the more clogged their arteries seem to become. Johnson, E. J., McDonald, K., Caldarella, S. M., Chung, H. Y., Troen, A. M., and Snodderly, D. M. Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. View abstract. 2013 Jul;131(7):843-50. Eye Disease Case-Control Study Group. 2012;56(1):126-146. Giordano, P., Scicchitano, P., Locorotondo, M., Mandurino, C., Ricci, G., Carbonara, S., Gesualdo, M., Zito, A., Dachille, A., Caputo, P., Riccardi, R., Frasso, G., Lassandro, G., Di, Mauro A., and Ciccone, M. M. Carotenoids and cardiovascular risk. Cho E, Seddon JM, Rosner B, et al. Schalch, W., Cohn, W., Barker, F. M., Kopcke, W., Mellerio, J., Bird, A. C., Robson, A. G., Fitzke, F. F., and van Kuijk, F. J. Xanthophyll accumulation in the human retina during supplementation with lutein or zeaxanthin - the LUXEA (LUtein Xanthophyll Eye Accumulation) study. View abstract. Oncotarget 2017;8(2):2391-9. Several studies 2012;32(6):418-424. Am.J.Clin.Nutr. Brown L, Rimm EB, Seddon JM, et al. View abstract. Tan AC, Balaratnasingam C, Yannuzzi LA. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. View abstract. Cancer Epidemiol.Biomarkers Prev. Pickup & Same Day Delivery available on most store items. Rock, C. L., Thornquist, M. D., Neuhouser, M. L., Kristal, A. R., Neumark-Sztainer, D., Cooper, D. A., Patterson, R. E., and Cheskin, L. J. PLoS One 2019;14(12):e0227048. View abstract. 2013;73(2):236-45. Loughman, J., Nolan, J. M., Howard, A. N., Connolly, E., Meagher, K., and Beatty, S. The impact of macular pigment augmentation on visual performance using different carotenoid formulations. Upritchard, J. E., Schuurman, C. R., Wiersma, A., Tijburg, L. B., Coolen, S. A., Rijken, P. J., and Wiseman, S. A. Vitamin D: 2 people, 18.18%. Nutrients 2017;9(11):1246. Cancer Causes Control 1991;2:325-57. Holtan, S. G., O'Connor, H. M., Fredericksen, Z. S., Liebow, M., Thompson, C. A., Macon, W. R., Micallef, I. N., Wang, A. H., Slager, S. L., Habermann, T. M., Call, T. G., and Cerhan, J. R. Food-frequency questionnaire-based estimates of total antioxidant capacity and risk of non-Hodgkin lymphoma. Tan, J. S., Wang, J. J., Flood, V., Rochtchina, E., Smith, W., and Mitchell, P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Just like many other types of antioxidants, it is found in brightly colored foods like fruits and vegetables especially leafy greens and types that are deep orange or yellow. Lutein, zeaxanthin, macular pigment, and visual function in adult cystic fibrosis patients. View abstract. A 2009 study conducted on diabetic rats found that supplementing with lutein and DHA (a crucial type of omega-3 fatty acid) helped normalize all diabetes-induced biochemical modifications. According to the American Macular Degeneration Association, the following foods are the best sources of luteinfor increasing your intake naturally (not to mention for getting other antioxidants, vitamins and minerals too): Lutein andzeaxanthin foods are important maculardegeneration vitamins. The supplement used is a product of Wakamoto Pharmaceutical. Garcia-Closas, R., Agudo, A., Gonzalez, C. A., and Riboli, E. Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain. Am J Clin Nutr 2008;87(5):1521-1529. Nutrients. Dosage of Lutein Suggested Dosing 6-20 mg/day For an eye disease called age-related macular degeneration ( AMD ): 6-12 mg of lutein daily, either through diet or Xiong K, Zhao Y, Hu S, Ma A, Ma Y. Dose-response relationship between oral lutein intake and plasma lutein concentration: A randomized controlled trial. Br.J.Nutr. 2012;107(3):350-359. 2012;70(4):234-240. Ma L, Liu R, Du JH, et al. View abstract. A., Kardinaal, A. F., Van, Poppel G., and Van, Norren D. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Carcinogenesis 1997;18(9):1847-1850. 2008;49(8):3328-3335. View abstract. 2014 Jan 22;6(1):452-65. View abstract. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. 1996;126(9):2098-2106. View abstract. The following vitamins and minerals are particularly relevant for eczema: Zinc: Found in seafood, pumpkin seeds, dark choc, lean red meat Vitamin C: Found in brightly Bahrami, H., Melia, M., and Dagnelie, G. Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]. A., de Vries, A. J., Goldbohm, R. A., Tijburg, L. B., Kardinaal, A. F., and van Poppel, G. Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin. View abstract. Br J Nutr 2001;85(2):227-238. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degermation: the Veterans LAST study (Lutein Antioxidant Supplement Trial). Garca-Layana A, Recalde S, Alamn AS, Robredo PF. Kiokias, S. and Gordon, M. H. Dietary supplementation with a natural carotenoid mixture decreases oxidative stress. View abstract. View abstract. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Lutein and zeaxanthin status and risk of age-related macular degeneration. Astaxanthin supplementation does not attenuate muscle injury following eccentric exercise in resistance-trained men. 2 mg of copper. 2000;41(11):3322-3326. View abstract. Cota F, Costa S, Giannantonio C, Purcaro V, Catenazzi P, Vento G. Lutein supplementation and retinopathy of prematurity: a meta-analysis. 1997;6(8):617-623. 2012;56(6):866-877. Similarly, other studies show that higher dietary intakes ofzeaxanthin and lutein along with other natural antioxidants, includingvitamin C,beta-caroteneandvitamin E, are associated with a significantly decreased risk of cataract formation. For people with a genetic predisposition to eye disorders or cancer, taking more lutein might be necessary. View abstract. 2000;41(5):1200-1209. This raises the risk for arteriosclerosis development and clogging of the carotid arteries that can lead to heart attacks. Ophthalmologica 2017;237(3):159-66. View abstract. Int J Vitam Nutr Res 1998;68:360-5. 1996;36(13):2001-2012. 1995;36(12):2531-2541. Nussbaum, J. J., Pruett, R. C., and Delori, F. C. Historic perspectives. Br.J.Ophthalmol. Cancer Sci. Correlates of serum lutein + zeaxanthin: findings from the Third National Health and Nutrition Examination Survey. View abstract. JAMA 1994;272:1413-20. 2006;82(5):915-920. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Lutein has no known severe, serious, moderate, or mild interactions with other drugs. This information does not contain all possible interactions or adverse effects. Nutrition 2003;19(1):21-24. Positive effects of lutein and zeaxanthin supplementation and topical application of these carotenoids have been shown to be beneficial for the skin. Front Nutr 2022;9:924997. Invest Ophthalmol.Vis.Sci. Ophthalmology 2002;109:2272-8.. View abstract. Dietary intake of antioxidants and risk of age-related macular degeneration. Wolf-Schnurrbusch UE, Zinkernagel MS, Munk MR, Ebneter A, Wolf S. Oral lutein supplementation enhances macular pigment density and contrast sensitivity but not in combination with polyunsaturated fatty acids. Chasan-Taber L, Willett WC, Seddon JM, et al. J Natl.Cancer Inst. J Epidemiol Community Health 1998;52:468-72. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Rosenthal, J. M., Kim, J., de, Monasterio F., Thompson, D. J., Bone, R. A., Landrum, J. T., de Moura, F. F., Khachik, F., Chen, H., Schleicher, R. L., Ferris, F. L., III, and Chew, E. Y. Dose-ranging study of lutein supplementation in persons aged 60 years or older. 2007;125(9):1225-1232. 2002;74(3):371-381. Int J Vitam.Nutr Res. Aside from protecting eyes, lutein uses also include helping prevent skin disorders, several types of cancer including colon or breast cancer, type 2 diabetes, and risk factors associated with coronary heart disease. 2015 Aug 25;314(8):791-801. Teikari JM, Rautalahti M, Haukka J, et al. Medicine (Baltimore) 2019;98(29):e15404. Graefes Arch Clin Exp Ophthalmol. J.Nutr. Kobayashi J, Tominaga E, Ozeki M, Okubo T, Nakagawa K, Miyazawa T. Randomized controlled trial of a water-soluble formulation of lutein in humans. Xu J, Song C, Song X, Zhang X, Li X. Carotenoids and risk of fracture: a meta-analysis of observational studies. The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial. Lutein and its relative zeaxanthin are pigments called carotenoids. The possible significance of parallel changes in plasma lutein and retinol in Pakistani infants during the summer season. Spraycar M, ed. A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. To give you some inspiration, here are several recipes to help you out: Lutein appears to be nontoxic and safe for consumption in moderate or even relatively high doses. 2011;52(11):8174-8178. Am.J Clin.Nutr 1996;64(4):594-602. Am J Clin Nutr 2016;103(2):481-94. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Plasma antioxidant vitamins and carotenoids and age-related cataract. 2006;124(8):1151-1162. View abstract. Intakes of Lutein, Zeaxanthin, and Other Carotenoids and Age-Related Macular Degeneration During 2 Decades of Prospective Follow-up. J Am Optom Assoc 1999;70:39-47. View abstract. Acta Ophthalmol.Scand. View abstract. Am.J.Ophthalmol. Prog Retin Eye Res. View abstract. View abstract. View abstract. Serum carotenoids and tocopherols and severity of nuclear and cortical opacities. Ophthalmology 2003;110(1):51-60. An ancillary study of the women's health initiative. View abstract. Curr.Pharm.Des 2012;18(34):5577-5589. View abstract. Cui YH, Jing CX, Pan HW. Hammond, B. R., Jr. and Fletcher, L. M. Influence of the dietary carotenoids lutein and zeaxanthin on visual performance: application to baseball. Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies. It is thought to function as a light filter, protecting the eye tissues from sunlight damage. View abstract. View abstract. View abstract. View abstract. Invest Ophthalmol.Vis.Sci. A., Fisher, A. I., Klein, R., Palta, M., Block, G., Millen, A. E., and Wright, J. D. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Lutein is an orange-colored nutrient. het Hof, K. H., Tijburg, L. B., Pietrzik, K., and Weststrate, J. Ophthalmology 2008;115(5):876-883. View abstract. 2002;132(12):3668-3673. Design: Subjects were 1290 mother-child pairs in an ongoing cohort study. The risk of vision loss decreased by 19%. View abstract. Long-term supplementation with alpha-tocopherol and beta-carotene and age-related cataract. Mol.Nutr.Food Res. View abstract. Lyle, B. J., Mares-Perlman, J. Eye Disease Case-Control Study Group. Effects of supplemental beta-carotene , cigarette smoking, and alcohol consumption on serum carotenoids in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Nicknamed the eye vitamin, lutein is a type of carotenoid antioxidant that is most well-known for protecting eye health. View abstract. View abstract. View abstract. WebOverview. Molecules. View abstract. Cancer Epidemiol.Biomarkers Prev. J Aging Res 2019;2019:3709402. Johnson, E. J. View abstract. Dreher, M. L. Pistachio nuts: composition and potential health benefits. Malila, N., Virtamo, J., Virtanen, M., Pietinen, P., Albanes, D., and Teppo, L. Dietary and serum alpha-tocopherol, beta-carotene and retinol, and risk for colorectal cancer in male smokers. A., Snodderly, D. M., Klein, M. L., Wooten, B. R., and Chappell, R. Macular pigment density and age-related maculopathy in the Carotenoids in Age-Related Eye Disease Study. View abstract. Hu, F., Wang, Yi B., Zhang, W., Liang, J., Lin, C., Li, D., Wang, F., Pang, D., and Zhao, Y. Carotenoids and breast cancer risk: a meta-analysis and meta-regression. Bartlett, H. E. and Eperjesi, F. A randomised controlled trial investigating the effect of lutein and antioxidant dietary supplementation on visual function in healthy eyes. Public Health Nutr 2020:1-8. are clickable links to medically peer-reviewed studies. View abstract. Effect of the main dietary antioxidants (carotenoids, gamma-tocopherol, polyphenols, and vitamin C) on alpha-tocopherol absorption. Fitzgerald KC, O'Reilly J, Fondell E, et al. Manzoni P, Guardione R, Bonetti P, et al. 5 Reasons to Add Lamb Meat to Your Diet, St. Johns Wort Benefits for Depression, PMS & Menopause. View abstract. Weigert, G., Kaya, S., Pemp, B., Sacu, S., Lasta, M., Werkmeister, R. M., Dragostinoff, N., Simader, C., Garhofer, G., Schmidt-Erfurth, U., and Schmetterer, L. Effects of lutein supplementation on macular pigment optical density and visual acuity in patients with age-related macular degeneration. 2012;96(5):1161S-1165S. 2000;46(11):1818-1829. Invest Ophthalmol.Vis.Sci. View abstract. 2009;40(6):1047-1054. Thyagarajan, B., Meyer, A., Smith, L. J., Beckett, W. S., Williams, O. D., Gross, M. D., and Jacobs, D. R., Jr. Serum carotenoid concentrations predict lung function evolution in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Br.J.Nutr. Berendschot, T. T., Broekmans, W. M., Klopping-Ketelaars, I. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am.J.Clin.Nutr. View abstract. Siems, W. G., Sommerburg, O., and van Kuijk, F. J. Lycopene and beta-carotene decompose more rapidly than lutein and zeaxanthin upon exposure to various pro-oxidants in vitro. 2-15-2007;458(2):128-135. van den Berg H. Effect of lutein on beta-carotene absorption and cleavage. Since the plant Our team aims to be not only thorough with its research, but also objective and unbiased. View abstract. Are supplements really necessary to achieve benefits? Liver Cleanse | Lutein Benefits, Uses, Foods, Side Effects and More - Dr View abstract. Am J Clin Nutr 2000;71:950-5. View abstract. Clin Nutr 2016;35(1):109-16. B., Hansen, R. M., Ashmeade, T. L., Oliver, J. S., Mackey, A. D., Dimmit, R. A., Hartmann, E. E., and Adamkin, D. H. Effect of carotenoid supplementation on plasma carotenoids, inflammation and visual development in preterm infants. Giving preterm infants lutein and zeaxanthin by mouth doesn't prevent retinopathy of prematurity. Invest Ophthalmol.Vis.Sci. View abstract. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. Am J Clin Nutr 2003;78(5):985-992. are clickable links to these studies. Dani, C., Lori, I., Favelli, F., Frosini, S., Messner, H., Wanker, P., De, Marini S., Oretti, C., Boldrini, A., Massimiliano, C., Bragetti, P., and Germini, C. Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurity: a randomized controlled study. 2004;3(6):310-316. JAMA Ophthalmol 2015;133(12):1415-24. Influence of feeding different vegetables on plasma levels of carotenoids, folate and vitamin C. Effect of disruption of the vegetable matrix. Always check with your doctor before you use a natural product. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. While we dont know exactly how lutein and cancer formation is tied just yet, correlational studies have shown that adults with higher levels of lutein in the blood experience a reduced risk of developing several forms of common cancers. Evans JR, Lawrenson JG. View abstract. 2003;133(4):992-998. 2020;12(10):2966. Gartner, C., Stahl, W., and Sies, H. Preferential increase in chylomicron levels of the xanthophylls lutein and zeaxanthin compared to beta-carotene in the human. View abstract. Ito, Y., Wakai, K., Suzuki, K., Tamakoshi, A., Seki, N., Ando, M., Nishino, Y., Kondo, T., Watanabe, Y., Ozasa, K., and Ohno, Y. Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study. View abstract. Changes in plasma amino acid patterns in chronic alcoholic patients during ethanol withdrawal syndrome: their clinical implications. Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy. 2003;94(1):57-63. Plant foods and colon cancer: an assessment of specific foods and their related nutrients (United States). Ma, L., Dou, H. L., Wu, Y. Q., Huang, Y. M., Huang, Y. Kim MK, Ahn SH, Lee-Kim. Goodman, M. T., Kiviat, N., McDuffie, K., Hankin, J. H., Hernandez, B., Wilkens, L. R., Franke, A., Kuypers, J., Kolonel, L. N., Nakamura, J., Ing, G., Branch, B., Bertram, C. C., Kamemoto, L., Sharma, S., and Killeen, J. Nutr Res 2001;21:797-809. Am.J.Clin.Nutr. Vorgerd M, Grehl T, Jager M, et al. View abstract. Djuric, Z., Uhley, V. E., Naegeli, L., Lababidi, S., Macha, S., and Heilbrun, L. K. Plasma carotenoids, tocopherols, and antioxidant capacity in a 12-week intervention study to reduce fat and/or energy intakes. The ARIC Study Investigators. View abstract. Flood, V., Rochtchina, E., Wang, J. J., Mitchell, P., and Smith, W. Lutein and zeaxanthin dietary intake and age related macular degeneration. Qiu Z, Chen X, Geng T, et al. 2006;6:23. Am J Clin Nutr 2004;80:1508-20. Acta Ophthalmol. J.Nutr. Skin Pharmacol.Physiol 2007;20(4):199-210. Pool-Zobel, B. L., Bub, A., Muller, H., Wollowski, I., and Rechkemmer, G. Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. J Nutr 1997;127:1636S-45S. Lai JS, Veetil VO, Lanca C, et al. Lutein has earned the nickname the eye vitamin because itswell-known for protecting eye health. Schupp C, Olano-Martin E, Gerth C, et al. Duncan, J. L., Aleman, T. S., Gardner, L. M., De Castro, E., Marks, D. A., Emmons, J. M., Bieber, M. L., Steinberg, J. D., Bennett, J., Stone, E. M., MacDonald, I. M., Cideciyan, A. V., Maguire, M. G., and Jacobson, S. G. Macular pigment and lutein supplementation in choroideremia. 2014 May;174(5):763-71. Br J Nutr 2021;126(7):1028-1039. View abstract. View abstract. Cancer Epidemiol.Biomarkers Prev. You already know that filling up on plenty of fruits and veggies is good for you, and heres just another example of why that is. The pharmacological effects of quercetin, such as its antioxidant, anti-inflammatory, antiallergic, antiaging, and anticancer activities, as well as its regulating effect on interleukin (IL)-6, IL-8, tumor necrosis factor (TNF), histamine, and tryptase release in mast cells, are well acknowledged [9]. Olmedilla, B., Granado, F., Blanco, I., and Vaquero, M. Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study. View abstract. Eichler, O., Sies, H., and Stahl, W. Divergent optimum levels of lycopene, beta-carotene and lutein protecting against UVB irradiation in human fibroblastst. The major reason the lens becomes cloudy is damage due to oxidation. Broekmans, W. M., Berendschot, T. T., Klopping-Ketelaars, I. 2005 - 2023 WebMD LLC. 2008;32(2):351-353. Curran-Celentano, J., Hammond, B. R., Jr., Ciulla, T. A., Cooper, D. A., Pratt, L. M., and Danis, R. B. 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