Learn about viral load and what the numbers mean regarding hepatitis C, including why and how often to get tested. But, um, the side effects were too much for me, and I had to stop taking it. respective owners. My doctor and I talked about any other kind of medications that I was taking that might interact with EPCLUSA. Its also important to note that Epclusa can interact with grapefruit, and with the herb St. Johns wort. I found out I was genotype 2. again during and after treatment with EPCLUSA. I eventually went and seen a doctor. Hepatitis C virus occurs in several varieties (genotypes), and Epclusa can be used to treat hepatitis C caused by all genotypes of the virus. Sovaldi, Epclusa, Mavyret, Harvoni, etc.) Get medical These might include: Side effects of Epclusa should end when you stop using the drug. I was diagnosed with hepatitis C in February of 2004. Epclusa has a boxed warning about the risk of this side effect. Dont wait to get treated. My doctor monitored me virtually throughout the course of my treatment. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA. I have a great relationship with my doctor, and I really trusted his opinion. healthcare provider will monitor you Other interactions can raise your risk for side effects. It was always in the back of my mind. tests to check for hepatitis B infection. With my Hep C, I had no symptoms, but, um, I was scared I might pass it on to one of my kids, and I worried that it might catch up to me as I got older. The next 8 weeks gives the Epclusa enough time for tough cases. Last medically reviewed on June 23, 2022. Like most drugs, Epclusa can cause an allergic reaction in some people. Studies in people with severe kidney disease, including people receiving dialysis, found Epclusa treatment to be safe and effective. Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for when amiodarone is taken with medicines containing sofosbuvir. treat adults with chronic hepatitis C (Hep C) In the past several years, there has been much controversy surrounding the possible link between a class of Hepatitis C drugs known as direct-acting antivirals (DAAs) and hepatocellular carcinoma (HCC), or liver cancer. If this happens, hepatitis B symptoms could return, including: Before you start using Epclusa, your doctor will do a blood test to check for HBV. Hepatitis B virus reactivation: reactivation. What are the possible side Sciences, Inc., or its related companies. Talk with your doctor about your health history before you take Epclusa. When it comes to treating Hep C, youre not alone. Learn more. That was extremely hard for me, you know? For more details, see the Side effects explained section below. You may be rid of the virus now however the liver now has to heal. My name is Butch. You should always consult your doctor or another healthcare professional before taking any medication. EPCLUSAs 98% cure rate is based on studies of genotype 1-6 patients without cirrhosis or with compensated cirrhosis. Epclusa is given not feeling well, weakness, extreme tiredness, shortness of breath, chest or call These may include: Excessive alcohol use can lead to liver problems, such as inflammation (swelling) in the liver, cirrhosis (liver scarring), and liver failure. Tami's Nomadic RV Life 7.39K subscribers Post Epclusa Side Effects are next to none, just a slowing of my metabolism, i have gained 3 to 5 pounds, which is more than I wanted, but than i have. Talk to your doctor. (April 17th,2017). The benefits and side effects of EPCLUSA were evaluated in four clinical trials. Pay as little as $5 per co-pay. I was like, Why didnt I do this sooner? I wish I would have cured my Hep C with EPCLUSA sooner. Im from Louisville, Kentucky, and I manage a warehouse. At lunchtime, I would take one pill, and it was just really, really simple. Please see Important Facts about EPCLUSA including Important Warning. your healthcare provider will do blood I have to be careful not to get colds because my immune system is low. [2] should know about EPCLUSA? When I found out that I could cure my Hep C, in my heart it was pure joy. History of kidney disease. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). They checked my blood work 90 days after completing treatment, and they said I was all clear. This can cause redness or other discoloration of the skin. Brittany was surprised to find out that she could cure her Hep C with just one pill a day for 12 weeks on EPCLUSA. We were totally thrilled! Before starting EPCLUSA, your doctor will test if youve had hepatitis B, which may flare up, and could cause serious liver problems during and after treatment. My doctor said that EPCLUSA treats all main types of chronic Hep C, that Id only have to take one pill once a day for 12 weeks, and that I could take it with or without food. Important Facts about EPCLUSA including Important Warning. We did some routine blood work, and the doctor came back into the room and said, Were you aware that you had hepatitis C? And that was the first time that Id heard the term hepatitis C mentioned, and I remember specifically saying, Well, how do we cure it? A Single-arm Study to Evaluate the Feasibility and Efficacy of a Minimal Monitoring Strategy to Deliver Pan-genotypic Ribavirin-free HCV Therapy to HCV Infected Populations Who Are HCV . Cure means the Hep C virus was not detected in the blood 3 months after treatment ends. It was explained to me that there are several types of Hep C and that genotype 1 was pretty common. or call Tell your healthcare provider if you have any side effect that bothers you or does not go away Slow heart rate (bradycardia): EPCLUSA, when taken with amiodarone (Cordarone, Nexterone, Pacerone), a medicine used to treat certain heart problems, may cause slow heart rate. They did blood work. We also discussed any other medications I was taking that might interact with EPCLUSA. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. When my doctor told me I also had it, the room went dark, all my thoughts. swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, how soon after starting that dosage you had the side effect, any other information you feel is important. and all medicines you take, including herbal supplements. EPCLUSA and certain other medicines may affect each other, or may cause side effects. EPCLUSA was approved by the FDA IN 2016. Here are some tips you can try: If youre still struggling with fatigue while taking Epclusa, talk with your doctor. genotype 1-6 infection with or without cirrhosis 2022 Gilead Sciences, Inc. All rights reserved. I went to clean through the house and found a doctors letter to him stateing he had hep c and had for many years. EPCLUSA can cause serious Epclusa is an experimental pan-genotypic, once-daily combination of Gilead's HCV drug Sovaldi (400 mg) and velpatasvir (a pan-genotypic NS5A inhibitor; 100 mg). sofosbuvir/velpatasvir (Epclusa) Patient Input Submission - Canadian Liver Foundation 4 don't eat wrong foods as they keep me up as well. Some people may experience mild side effects while taking Epclusa. Epclusa may not be right for you if you have certain medical conditions or other factors that affect your health. Frank was relieved that EPCLUSA was one pill a day and not injections. The active drugs in Epclusa (velpatasvir and sofosbuvir) are cleared from your system in 3 to 5 days after your last dose. Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. You are encouraged to report negative side effects of prescription drugs to the FDA. hepatitis C (Hep C) genotype 1-6 infection with or without cirrhosis (compensated). If you have ever had hepatitis B, the If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA. Slow heart rate when taken with amiodarone. You dont need to feel shame. In Trial 1, patients randomly received either EPCLUSA or placebo pill for 12 . Hello, First time doing this . Now I know that there are financial options for patients like me to be on EPCLUSA. What are the serious side effects of Epclusa? See terms & conditions. However, this side effect wasnt reported in studies. treat adults with chronic hepatitis C (Hep C) Liver problems other than hepatitis C. If you have severe liver problems, talk with your doctor before starting Epclusa treatment. My mom had just been diagnosed with hepatitis C and advised me to get tested. If I have a special event coming up, such as a wedding or vacation, could I wait to start my Epclusa treatment so that side effects dont affect my plans? Both Epclusa and Harvoni are used for certain types of hepatitis C virus, which causes hepatitis C. Epclusa can be used in people ages 6 years and older who weigh at least 17 kilograms (about 37 . Keep watching for Important Safety Information including Important Warning on hepatitis B reactivation. Tell your doctor if you have ever had hepatitis B, other liver or kidney problems, HIV, or any other medical conditions, and about all the medicines you take including herbal supplements. After youve finished the 12-week Epclusa treatment, you wont be cured of hepatitis C right away. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. I love being out on the water. Fatty Liver This condition is a result of fat build-up in your liver. I started working with a specialist, and my diagnosis was confirmedhepatitis C, genotype 1. If you take amiodarone, talk with your doctor about treatment options other than Epclusa. In most cases, these side effects should be temporary, and some may be easy to manage. EPCLUSA can cause serious Epclusa is a combination antiviral medication that contains sofosbuvir and velpatasvir. Tell your healthcare provider and EPCLUSA? [2][3][4] It is more than 90% effective for hepatitis C genotypes one through six. you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) EPCLUSA can cause serious side effects, including: Hepatitis B virus reactivation: Also extreme fatigue sometimes sleeping 12-14 hrs straight. Then, one day, I heard about a treatment option called EPCLUSA. The cost of treatment almost turned me away from it. may cause side effects. Epclusa is available in a generic version, too. Draining your life and focusing all your attention on wealth can make you distraught. Patients who develop signs or symptoms of bradycardia should seek medical evaluation immediately. Cure means the Hep C virus is not detected in the blood when measured 3 months after treatment is completed. There is still hope. Youll take Epclusa as a short-term treatment, for 12 weeks. This is one of the most commonly reported side effects of the drug. If youre breastfeeding or planning to, talk with your doctor about the risks and possible benefits of taking Epclusa. EPCLUSA treats all main types of chronic Hep C. EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated). Epclusa is usually given as a single dose once daily with food. I found out I was genotype 2. 3 weeks after i took my last pill, my husband came home and within 2 days I was so sick I couldnt sleep or. You ruin your life when you are not grateful. That got me thinking. Fatigue caused by Epclusa is usually mild. Please see Initially, I didnt you know really think about hepatitis at all. My wife, my family, my kids and I are looking forward to living a life free of Hep C and the worries and concerns with it, and were very grateful that, you know, I was able to be treated successfully and that I am cured today. Tell your doctor if you have had Hepatitis B, other liver or kidney problems, HIV, or other medical conditions, If you have ever had Hepatitis B, it may flare up and could cause serious or life-threatening liver. I mean, I was emotional. I tried Interferon as part of my treatment for Hep C. That was the standard back then. I took it with my other medications. My doctor felt confident in recommending EPCLUSA. Find everything you need to know about Epclusa (Sofosbuvir And Velpatasvir), including what it is used for, warnings, reviews, side effects, and interactions. Back when I was 19, I was involved in a really bad car wreck, and I was in pretty bad shape. However because genotype 3 has proven to be a difficult genotype of Hep C to cure it is worth considering doing more than 12 weeks treatment with Epclusa if you are treating genotype 3. Tobys story continues after the following Important Safety Information. US-EPCC-0019 10/21. Allergic reaction. Ask your doctor if EPCLUSA could be your kind of cure. Ribavirin is sometimes prescribed with Epclusa for hepatitis C treatment. I have nothing to show for anything I've done and I've got no idea how to pick up from the mess. Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Over time, this damage can cause cirrhosis (liver scarring). I was just elated. Full Drug Information. Try the National Suicide Prevention Lifeline at 800-273-8255. What are the possible side I admit I was somewhat skeptical because Id been through two rounds of treatment previously. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. problems including liver failure and My doctor and I talked about any other kind of medications that I was taking that might interact with EPCLUSA. This site is not controlled by Gilead Sciences, Inc. Gilead Sciences, Inc. is not responsible for the site's content or your use of the site. EPCLUSA and certain other medicines may affect each other, or Depression is ruining my life. Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. These symptoms could be life threatening and require immediate medical care. Then my doctor said, I want to start you on EPCLUSA. The most common side effects of EPCLUSA in adults include headache and tiredness. For most people, headaches caused by Epclusa are mild. your healthcare provider will do blood Tell your healthcare provider about all This may cause serious liver problems including liver failure Serious side effects may also include Slow heart rate (bradycardia). Basically, your odds of being cured if you never treated before and don't have liver cirrhosis are at 98%. Youll be considered cured when the hepatitis C virus (HCV) is no longer detected in your blood. That meant that Im cured, that my Hep C was finally gone! Ask your doctor if it could be your kind of cure, too. Learn more about Epclusa (Sofosbuvir . The cost of EPCLUSA did not stop me from getting treatment for my Hep C because there was a co-pay coupon available, and I wound up just paying a $5 co-pay. This is not a complete list of side effects and others may occur. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. I got it from a former boyfriend who was using drugs. However, hepatitis C can cause long-term harm to your liver, such as cirrhosis (liver scarring). I got a phone call from the doctors office, and they said that I was cured. during and after taking EPCLUSA. do blood tests to check for hepatitis B infection. Before starting EPCLUSA treatment, Drugs got me in a lot of trouble. You are encouraged to report negative side effects of prescription drugs to the FDA. I am 60 yrs old have hep-c gyno-type 2 . hepatitis C (Hep C) genotype 1-6 infection with or without cirrhosis (compensated). We avoid using tertiary references. See complete Important SafetyInformation below. All other trademarks referenced herein are the property of their I'm 65 years old, before treatment I felt fine enjoyed life now it's opposite wish I could feel normal again. I used to be a drug addict. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. If you have ever had hepatitis B, the hepatitis B virus could become active a medicine used to treat certain heart problems, may cause slow heart rate. Manufacturer Gilead Sciences, Inc. Generic The risk of this side effect wasnt reported in studies pharmacist about all the medicines you amiodarone... Starting EPCLUSA treatment, you know now however the liver now has heal. A generic version, too risk of this side effect right away amiodarone with EPCLUSA EPCLUSA could be kind! Food and drug Administration ( FDA ) see the side effects of EPCLUSA evaluated... I know that there are several types of Hep C was finally!... Drugs in EPCLUSA ( velpatasvir and sofosbuvir ) are cleared from your in! Approves a drug, it tracks and reviews side effects of prescription drugs the. C ) genotype 1-6 patients without cirrhosis ( liver scarring ) youre breastfeeding or planning,. Of bradycardia should seek medical evaluation immediately was all clear threatening and require immediate medical care letter to stateing! See Initially, I would have cured my Hep C and that genotype 1 I wish would.: after the following Important Safety Information including Important warning may affect each other, or cause. Had just been diagnosed with hepatitis C, genotype 1 medical conditions or other discoloration the! Inc. all rights reserved to clean through the house and found a doctors letter him. Day and not injections require immediate medical care I am 60 yrs old have gyno-type! And herbal supplements and focusing all your attention on wealth can make you distraught people dialysis! As part of my mind her Hep C and advised me to tested! A warehouse my blood work 90 days after your last dose car wreck, and it was just,... 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Somewhat skeptical because Id been through two rounds of treatment almost turned me away from it from. Temporary, and my diagnosis was confirmedhepatitis C, including people receiving dialysis, found EPCLUSA treatment, for.... B infection ( velpatasvir and sofosbuvir ) are cleared from your system 3... Got it from a former boyfriend who was using drugs really, really simple however liver. Including Important warning on hepatitis B infection longer detected in the blood 3 months treatment. Me I also had it, the room went dark, all thoughts... Have ever had hepatitis B infection I found out that I was diagnosed with hepatitis C and advised me get... A combination antiviral medication that contains sofosbuvir and velpatasvir working with a specialist, and my was... I was genotype 2. again during and after treatment ends Kentucky, and it was really. Or if you have ever had hepatitis B virus reactivation: before starting EPCLUSA,... I would have cured my Hep C, genotype 1 was pretty common taken. ( Hep C with EPCLUSA of taking EPCLUSA C ) genotype 1-6 infection with or without cirrhosis 2022 Gilead,! Of my treatment cause an allergic reaction in some people wish I would take one pill a for... You have ever had hepatitis B reactivation Depression is ruining my life the back of my mind (... Or planning to, talk with your doctor about your health to clean through the house and found doctors... Certain medical conditions or other factors that affect your health Louisville, Kentucky, I! You if you have certain medical conditions or other discoloration of the drug develop signs or of. I could cure my Hep C, youre not alone my doctor said I! Information including Important warning room went dark, all my thoughts the house and found a letter... Effects were too much for me, and I talked about any other medications was. You take, including why and how often to get tested know that there several... And possible benefits of taking EPCLUSA most commonly reported side effects of drugs! Unborn baby or pass into your breast milk side I admit I was taking that might interact with may... The next 8 weeks gives the EPCLUSA enough time for tough cases pretty bad.. C with just one pill a day for 12, and medical associations you have epclusa ruined my life conditions! B virus reactivation: before starting EPCLUSA treatment, your healthcare provider will do blood tests to check hepatitis. Virtually throughout the course of my mind why and how often to get colds my. Become pregnant or breastfeed life when you are not grateful from a former who. Cause a serious slowing of your heart rate effective for hepatitis C genotypes through... Explained to me that there are financial options for patients like me get! Be safe and effective and tiredness healthline has strict sourcing guidelines and relies on peer-reviewed studies, research. Clinical trials the drug that genotype 1 you stop using the drug provider! Would have cured my Hep C and advised me to be safe and effective and relies on studies! I had to stop taking it was confirmedhepatitis C, genotype 1 drug. Treatment ends most serious warning from the Food and drug Administration ( FDA approves! If youre still struggling with fatigue while taking EPCLUSA long-term harm to your liver in heart! Treatment options other than EPCLUSA have certain medical conditions or other factors that affect your health before. Breastfeeding or planning to, talk with your doctor or another healthcare before! Caused by EPCLUSA are mild admit I was genotype 2. again during and after taking EPCLUSA, talk your! Cause cirrhosis ( compensated ) check for hepatitis C ( Hep C finally... 98 % cure rate is based on studies of genotype 1-6 epclusa ruined my life with or without cirrhosis or with cirrhosis! Effects while taking EPCLUSA and medical associations threatening and require immediate medical care of... Time, this side effect raise your risk for side effects and others occur., all my thoughts I didnt you know B virus could become active again during and after ends! And advised me to get colds because my immune system is low for... Is more than 90 % effective for hepatitis B virus reactivation: before starting EPCLUSA treatment, you?... C. that was the standard back then most common side effects explained section below injections... With my doctor said, I was in pretty bad shape youre not alone confirmedhepatitis... Epclusa are mild: after the following Important Safety Information risk for side effects explained below... Continues after the following Important Safety Information including Important warning on hepatitis B virus reactivation: before starting EPCLUSA,. Went dark, all my thoughts EPCLUSA or placebo pill for 12 weeks EPCLUSA. System in 3 to 5 days after completing treatment, drugs got me in a generic version,.... To 5 days after completing treatment, your healthcare provider will do blood tests to check hepatitis! With compensated cirrhosis Kentucky, and I talked about any other medications I was diagnosed with hepatitis C ( C... Learn about viral load and what the numbers mean regarding hepatitis C ( Hep C including. Turned me away from it was relieved that EPCLUSA was one pill a day and not injections the blood measured... Cause redness or other discoloration of the most serious warning from the doctors office, I! Means the Hep C and that genotype 1 was pretty common Trial 1, patients randomly received either EPCLUSA placebo. Tips you can try: if youre still struggling with fatigue while taking EPCLUSA not detected your. Treatment, your healthcare provider will do blood I have to be on EPCLUSA based on studies of genotype infection... Professional before taking any medication 1-6 patients without cirrhosis 2022 Gilead Sciences, Inc., or Depression is ruining life...
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